VMOZART wrote

I wonder if it is possible to close VPN site to site based router for Microsoft Azure. It is possible ? Which TP-Link model is prepared for this function.

Thanks and I look forward to returning.

Hi VMOZART

I don't know which type of VPN you meant. PPTP, L2TP, IPsec or others. I know that TP-Link VPN router supports PPTP, L2TP, IPsec site to site VPN. If Microsoft Azure also support these types of VPN, they should be able to establish. 

And sometimes you need to consider the NAT devices in front of your VPN devices.